Overexpression of P‐glycoprotein and resistance to Imatinib in chronic myeloid leukemia patients

BACKGROUND: The P‐glycoprotein (P‐gp) is one of the mechanisms of Imatinib (IM) resistance in chronic myeloid leukemia (CML). P‐gp has been identified as an efflux pump involved in releasing of IM outside CML cells. To date, the P‐gp involvement in the IM resistance development was not completely un...

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Detalhes bibliográficos
Publicado no:J Clin Lab Anal
Main Authors: Ammar, Mariam, Louati, Nour, Frikha, Imen, Medhaffar, Moez, Ghozzi, Hanen, Elloumi, Moez, Menif, Hela, Zeghal, Khaled, Ben Mahmoud, Lobna
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521244/
https://ncbi.nlm.nih.gov/pubmed/32715517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.23374
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