Overexpression of P‐glycoprotein and resistance to Imatinib in chronic myeloid leukemia patients

BACKGROUND: The P‐glycoprotein (P‐gp) is one of the mechanisms of Imatinib (IM) resistance in chronic myeloid leukemia (CML). P‐gp has been identified as an efflux pump involved in releasing of IM outside CML cells. To date, the P‐gp involvement in the IM resistance development was not completely un...

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Опубликовано в: :J Clin Lab Anal
Главные авторы: Ammar, Mariam, Louati, Nour, Frikha, Imen, Medhaffar, Moez, Ghozzi, Hanen, Elloumi, Moez, Menif, Hela, Zeghal, Khaled, Ben Mahmoud, Lobna
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521244/
https://ncbi.nlm.nih.gov/pubmed/32715517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.23374
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