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Cardioprotection by isosteviol derivate JC105: A unique drug property to activate ERK1/2 only when cells are exposed to hypoxia‐reoxygenation

In the present study, we have investigated potential cardioprotective properties of Isosteviol analogue we recently synthesized and named JC105. Treatment of heart embryonic H9c2 cells with JC105 (10 μM) significantly increased survival of cells exposed to hypoxia‐reoxygenation. JC105 (10 μM) activa...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Mohammed Abdul, Khaja Shameem, Rayadurgam, Jayachandra, Faiz, Neha, Jovanović, Aleksandar, Tan, Wen
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521240/
https://ncbi.nlm.nih.gov/pubmed/32794652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15721
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