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Mild hypoxia in vivo regulates cardioprotective SUR2A: A role for Akt and LDH

High-altitude residents have lower mortality rates for ischaemic heart disease and this is ascribed to cardiac gene remodelling by chronic hypoxia. SUR2A is a cardioprotective ABC protein serving as a subunit of sarcolemmal ATP-sensitive K(+) channels. The purpose of this study was to determine whet...

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Bibliografiske detaljer
Udgivet i:Biochim Biophys Acta
Main Authors: Mohammed Abdul, Khaja Shameem, Jovanović, Sofija, Du, Qingyou, Sukhodub, Andriy, Jovanović, Aleksandar
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Pub. Co 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547089/
https://ncbi.nlm.nih.gov/pubmed/25576887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2015.01.001
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