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Functional signatures of evolutionarily young CTCF binding sites

BACKGROUND: The introduction of novel CTCF binding sites in gene regulatory regions in the rodent lineage is partly the effect of transposable element expansion, particularly in the murine lineage. The exact mechanism and functional impact of evolutionarily novel CTCF binding sites are not yet fully...

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Publicat a:BMC Biol
Autors principals: Azazi, Dhoyazan, Mudge, Jonathan M., Odom, Duncan T., Flicek, Paul
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7520972/
https://ncbi.nlm.nih.gov/pubmed/32988407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-020-00863-8
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