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Dynamics, mechanisms, and functional implications of transcription factor binding evolution in metazoans

Transcription factor binding differences can contribute to organismal evolution by altering downstream gene expression programmes. Recent genome-wide studies in Drosophila and mammals have revealed common quantitative and combinatorial properties of in vivo DNA-binding, as well as significant differ...

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書誌詳細
主要な著者: Villar, Diego, Flicek, Paul, Odom, Duncan T
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175440/
https://ncbi.nlm.nih.gov/pubmed/24590227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg3481
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