Disease extent and anti‐tubercular treatment response correlates with Mycobacterium tuberculosis‐specific CD4 T‐cell phenotype regardless of HIV‐1 status

OBJECTIVES: The development of non‐sputum‐based assays for tuberculosis (TB) diagnosis and treatment monitoring is a key priority. Recent data indicate that whole blood‐based assays to assess the phenotype of Mycobacterium tuberculosis (Mtb)‐specific CD4 T cells hold promise for this purpose and req...

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Detalhes bibliográficos
Publicado no:Clin Transl Immunology
Main Authors: Riou, Catherine, Du Bruyn, Elsa, Ruzive, Sheena, Goliath, Rene T, Lindestam Arlehamn, Cecilia S, Sette, Alessandro, Sher, Alan, Barber, Daniel L, Wilkinson, Robert J
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7520805/
https://ncbi.nlm.nih.gov/pubmed/33005414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1176
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