Targeting IL‐5 pathway against airway hyperresponsiveness: A comparison between benralizumab and mepolizumab

BACKGROUND AND PURPOSE: Airway hyperresponsiveness (AHR) is a central abnormality in asthma. IL‐5 may modulate AHR in animal models of asthma, but the available data is inconsistent on the impact of targeting IL‐5 pathway against AHR. The difference between targeting IL‐5 or the IL‐5 receptor, α sub...

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Bibliographische Detailangaben
Veröffentlicht in:Br J Pharmacol
Hauptverfasser: Calzetta, Luigino, Ritondo, Beatrice Ludovica, Matera, Maria Gabriella, Facciolo, Francesco, Rogliani, Paola
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Research Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7520436/
https://ncbi.nlm.nih.gov/pubmed/32857420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15240
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