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Targeting IL‐5 pathway against airway hyperresponsiveness: A comparison between benralizumab and mepolizumab

BACKGROUND AND PURPOSE: Airway hyperresponsiveness (AHR) is a central abnormality in asthma. IL‐5 may modulate AHR in animal models of asthma, but the available data is inconsistent on the impact of targeting IL‐5 pathway against AHR. The difference between targeting IL‐5 or the IL‐5 receptor, α sub...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Calzetta, Luigino, Ritondo, Beatrice Ludovica, Matera, Maria Gabriella, Facciolo, Francesco, Rogliani, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7520436/
https://ncbi.nlm.nih.gov/pubmed/32857420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15240
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