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Integrating biological knowledge and gene expression data using pathway-guided random forests: a benchmarking study

MOTIVATION: High-throughput technologies allow comprehensive characterization of individuals on many molecular levels. However, training computational models to predict disease status based on omics data is challenging. A promising solution is the integration of external knowledge about structural a...

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Detaylı Bibliyografya
Yayımlandı:Bioinformatics
Asıl Yazarlar: Seifert, Stephan, Gundlach, Sven, Junge, Olaf, Szymczak, Silke
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7520048/
https://ncbi.nlm.nih.gov/pubmed/32399562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa483
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