Combination therapy with pemafibrate (K-877) and pitavastatin improves vascular endothelial dysfunction in dahl/salt-sensitive rats fed a high-salt and high-fat diet

BACKGROUND: Statins suppress the progression of atherosclerosis by reducing low-density lipoprotein (LDL) cholesterol levels. Pemafibrate (K-877), a novel selective peroxisome proliferator-activated receptor α modulator, is expected to reduce residual risk factors including high triglycerides (TGs)...

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Bibliographic Details
Published in:Cardiovasc Diabetol
Main Authors: Yoshida, Masatoki, Nakamura, Kazufumi, Miyoshi, Toru, Yoshida, Masashi, Kondo, Megumi, Akazawa, Kaoru, Kimura, Tomonari, Ohtsuka, Hiroaki, Ohno, Yuko, Miura, Daiji, Ito, Hiroshi
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Original Investigation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7520032/
https://ncbi.nlm.nih.gov/pubmed/32979918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-020-01132-2
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