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Interstitial macrophage-derived thrombospondin-1 contributes to hypoxia-induced pulmonary hypertension
AIMS: Transforming growth factor-β (TGF-β) signalling is required for chronic hypoxia-induced pulmonary hypertension (PH). The activation of TGF-β by thrombospondin-1 (TSP-1) contributes to the pathogenesis of hypoxia-induced PH. However, neither the cellular source of pathologic TSP-1 nor the downs...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cardiovasc Res |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Oxford University Press
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7519884/ https://ncbi.nlm.nih.gov/pubmed/31710666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvz304 |
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