CRISPR/Cas9‐mediated introduction of the sodium/iodide symporter gene enables noninvasive in vivo tracking of induced pluripotent stem cell‐derived cardiomyocytes

Techniques that enable longitudinal tracking of cell fate after myocardial delivery are imperative for optimizing the efficacy of cell‐based cardiac therapies. However, these approaches have been underutilized in preclinical models and clinical trials, and there is considerable demand for site‐speci...

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Udgivet i:Stem Cells Transl Med
Main Authors: Ostrominski, John W., Yada, Ravi Chandra, Sato, Noriko, Klein, Michael, Blinova, Ksenia, Patel, Dakshesh, Valadez, Racquel, Palisoc, Maryknoll, Pittaluga, Stefania, Peng, Kah‐Whye, San, Hong, Lin, Yongshun, Basuli, Falguni, Zhang, Xiang, Swenson, Rolf E., Haigney, Mark, Choyke, Peter L., Zou, Jizhong, Boehm, Manfred, Hong, So Gun, Dunbar, Cynthia E.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2020
Fag:
Enabling Technologies for Cell‐based Clinical Translation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519772/
https://ncbi.nlm.nih.gov/pubmed/32700830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.20-0019
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