HLA-G and HLA-F protein isoform expression in breast cancer patients receiving neoadjuvant treatment

The immunosuppressive human leukocyte antigens HLA-G and HLA-F are expressed on trophoblast and malignant cells. Four membrane-bound and three soluble HLA-G protein isoforms have been described, which have different immunosuppressive potentials. HLA-F has three transcript variants, resulting in thre...

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Pubblicato in:Sci Rep
Autori principali: Wuerfel, Franziska M., Huebner, Hanna, Häberle, Lothar, Gass, Paul, Hein, Alexander, Jud, Sebastian M., Hack, Carolin C., Wunderle, Marius, Schulz-Wendtland, Rüdiger, Erber, Ramona, Hartmann, Arndt, Ekici, Arif B., Beckmann, Matthias W., Fasching, Peter A., Ruebner, Matthias
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519664/
https://ncbi.nlm.nih.gov/pubmed/32978482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72837-3
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