Risk, Prediction and Prevention of Hereditary Breast Cancer – Large-Scale Genomic Studies in Times of Big and Smart Data

Over the last two decades genetic testing for mutations in BRCA1 and BRCA2 has become standard of care for women and men who are at familial risk for breast or ovarian cancer. Currently, genetic testing more often also includes so-called panel genes, which are assumed to be moderate-risk genes for b...

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Détails bibliographiques
Publié dans:Geburtshilfe Frauenheilkd
Auteurs principaux: Wunderle, Marius, Olmes, Gregor, Nabieva, Naiba, Häberle, Lothar, Jud, Sebastian M., Hein, Alexander, Rauh, Claudia, Hack, Carolin C., Erber, Ramona, Ekici, Arif B., Hoyer, Juliane, Vasileiou, Georgia, Kraus, Cornelia, Reis, André, Hartmann, Arndt, Schulz-Wendtland, Rüdiger, Lux, Michael P., Beckmann, Matthias W., Fasching, Peter A.
Format: Artigo
Langue:Inglês
Publié: Georg Thieme Verlag KG 2018
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986564/
https://ncbi.nlm.nih.gov/pubmed/29880983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/a-0603-4350
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