Neural progenitor cell pyroptosis contributes to Zika virus-induced brain atrophy and represents a therapeutic target

Mounting evidence has associated Zika virus (ZIKV) infection with congenital malformations, including microcephaly, which raises global alarm. Nonetheless, mechanisms by which ZIKV disrupts neurogenesis and causes microcephaly are far from being understood. In this study, we discovered direct effect...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: He, Zhenjian, An, Shu, Chen, Jiahui, Zhang, Shuqing, Tan, Chahui, Yu, Jianchen, Ye, Hengming, Wu, Yun, Yuan, Jie, Wu, Jueheng, Zhu, Xun, Li, Mengfeng
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519283/
https://ncbi.nlm.nih.gov/pubmed/32907937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2007773117
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