PTPN14 aggravates inflammation through promoting proteasomal degradation of SOCS7 in acute liver failure

Acute liver failure (ALF) is a rare but life-threatening systemic disorder. The innate immune regulation has an important role in this process; however, the specific mechanisms are not completely clear. Using the LPS + D-GalN-induced ALF mouse model, we found that the survival rate of PTPN14-deficie...

Full description

Saved in:
Bibliographic Details
Published in:Cell Death Dis
Main Authors: Fu, Beibei, Yin, Songna, Lin, Xiaoyuan, Shi, Lei, Wang, Yu, Zhang, Shanfu, Zhao, Qingting, Li, Zhifeng, Yang, Yanling, Wu, Haibo
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519157/
https://ncbi.nlm.nih.gov/pubmed/32978373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03014-7
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items