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PTPN14 aggravates inflammation through promoting proteasomal degradation of SOCS7 in acute liver failure
Acute liver failure (ALF) is a rare but life-threatening systemic disorder. The innate immune regulation has an important role in this process; however, the specific mechanisms are not completely clear. Using the LPS + D-GalN-induced ALF mouse model, we found that the survival rate of PTPN14-deficie...
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| Publicat a: | Cell Death Dis |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7519157/ https://ncbi.nlm.nih.gov/pubmed/32978373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03014-7 |
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