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A trimeric CrRLK1L-LLG1 complex genetically modulates SUMM2-mediated autoimmunity
Cell death is intrinsically linked with immunity. Disruption of an immune-activated MAPK cascade, consisting of MEKK1, MKK1/2, and MPK4, triggers cell death and autoimmunity through the nucleotide-binding leucine-rich repeat (NLR) protein SUMM2 and the MAPK kinase kinase MEKK2. In this study, we ide...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7519094/ https://ncbi.nlm.nih.gov/pubmed/32978401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18600-8 |
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