Neuraminidase-1 promotes heart failure after ischemia/reperfusion injury by affecting cardiomyocytes and invading monocytes/macrophages

Neuraminidase (NEU)1 forms a multienzyme complex with beta-galactosidase (β-GAL) and protective-protein/cathepsin (PPC) A, which cleaves sialic-acids from cell surface glycoconjugates. We investigated the role of NEU1 in the myocardium after ischemia/reperfusion (I/R). Three days after inducing I/R,...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Basic Res Cardiol
Main Authors: Heimerl, Maren, Sieve, Irina, Ricke-Hoch, Melanie, Erschow, Sergej, Battmer, Karin, Scherr, Michaela, Hilfiker-Kleiner, Denise
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2020
Teme:
Original Contribution
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519006/
https://ncbi.nlm.nih.gov/pubmed/32975669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-020-00821-z
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