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Identification of protein-protected mRNA fragments and structured excised intron RNAs in human plasma by TGIRT-seq peak calling

Human plasma contains > 40,000 different coding and non-coding RNAs that are potential biomarkers for human diseases. Here, we used thermostable group II intron reverse transcriptase sequencing (TGIRT-seq) combined with peak calling to simultaneously profile all RNA biotypes in apheresis-prepared...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Yao, Jun, Wu, Douglas C, Nottingham, Ryan M, Lambowitz, Alan M
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518892/
https://ncbi.nlm.nih.gov/pubmed/32876046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60743
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