Phosphatidylinositol 3-phosphate and Hsp70 protect Plasmodium falciparum from heat-induced cell death

Phosphatidylinositol 3-phosphate (PI(3)P) levels in Plasmodium falciparum correlate with tolerance to cellular stresses caused by artemisinin and environmental factors. However, PI(3)P function during the Plasmodium stress response was unknown. Here, we used PI3K inhibitors and antimalarial agents t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Lu, Kuan-Yi, Pasaje, Charisse Flerida A, Srivastava, Tamanna, Loiselle, David R, Niles, Jacquin C, Derbyshire, Emily
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2020
Gaiak:
Biochemistry and Chemical Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518890/
https://ncbi.nlm.nih.gov/pubmed/32975513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.56773
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