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Phosphatidylinositol 3-phosphate and Hsp70 protect Plasmodium falciparum from heat-induced cell death

Phosphatidylinositol 3-phosphate (PI(3)P) levels in Plasmodium falciparum correlate with tolerance to cellular stresses caused by artemisinin and environmental factors. However, PI(3)P function during the Plasmodium stress response was unknown. Here, we used PI3K inhibitors and antimalarial agents t...

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Podrobná bibliografie
Vydáno v:eLife
Hlavní autoři: Lu, Kuan-Yi, Pasaje, Charisse Flerida A, Srivastava, Tamanna, Loiselle, David R, Niles, Jacquin C, Derbyshire, Emily
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518890/
https://ncbi.nlm.nih.gov/pubmed/32975513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.56773
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