The epitranscriptomic writer ALKBH8 drives tolerance and protects mouse lungs from the environmental pollutant naphthalene

The epitranscriptomic writer Alkylation Repair Homolog 8 (ALKBH8) is a transfer RNA (tRNA) methyltransferase that modifies the wobble uridine of selenocysteine tRNA to promote the specialized translation of selenoproteins. Using Alkbh8 deficient (Alkbh8(def)) mice, we have investigated the importanc...

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Vydáno v:Epigenetics
Hlavní autoři: Leonardi, Andrea, Kovalchuk, Nataliia, Yin, Lei, Endres, Lauren, Evke, Sara, Nevins, Steven, Martin, Samuel, Dedon, Peter C., Melendez, J. Andres, Van Winkle, Laura, Zhang, Qing-Yu, Ding, Xinxin, Begley, Thomas J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2020
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518688/
https://ncbi.nlm.nih.gov/pubmed/32303148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2020.1750213
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