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Contribution of Pulmonary CYP-mediated Bioactivation of Naphthalene to Airway Epithelial Injury in the Lung

Previous studies have established that cytochrome P450 enzymes (CYPs) in both liver and lung are capable of bioactivating naphthalene (NA), an omnipresent air pollutant and possible human carcinogen, in vitro and in vivo. The aim of this study was to examine the specific contribution of pulmonary CY...

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Bibliografiska uppgifter
I publikationen:Toxicol Sci
Huvudupphovsmän: Kovalchuk, Nataliia, Zhang, Qing-Yu, Van Winkle, Laura, Ding, Xinxin
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7548286/
https://ncbi.nlm.nih.gov/pubmed/32974682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfaa114
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