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Contribution of Pulmonary CYP-mediated Bioactivation of Naphthalene to Airway Epithelial Injury in the Lung

Previous studies have established that cytochrome P450 enzymes (CYPs) in both liver and lung are capable of bioactivating naphthalene (NA), an omnipresent air pollutant and possible human carcinogen, in vitro and in vivo. The aim of this study was to examine the specific contribution of pulmonary CY...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Kovalchuk, Nataliia, Zhang, Qing-Yu, Van Winkle, Laura, Ding, Xinxin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7548286/
https://ncbi.nlm.nih.gov/pubmed/32974682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfaa114
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