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Drug metabolism and pharmacokinetics of praziquantel: A review of variable drug exposure during schistosomiasis treatment in human hosts and experimental models

Schistosomiasis control is heavily reliant on the drug praziquantel (PZQ), which is used as preventive chemotherapy as part of national helminth control strategies. Given the heavy reliance on PZQ for mass drug administration, there has been considerable research on the potential of parasites develo...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Zdesenko, Grace, Mutapi, Francisca
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518612/
https://ncbi.nlm.nih.gov/pubmed/32976496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008649
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