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Praziquantel for Schistosomiasis: Single-Drug Metabolism Revisited, Mode of Action, and Resistance

Schistosomiasis, a major neglected tropical disease, affects more than 250 million people worldwide. Treatment of schistosomiasis has relied on the anthelmintic drug praziquantel (PZQ) for more than a generation. PZQ is the drug of choice for the treatment of schistosomiasis; it is effective against...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Vale, Nuno, Gouveia, Maria João, Rinaldi, Gabriel, Brindley, Paul J., Gärtner, Fátima, Correia da Costa, José M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404606/
https://ncbi.nlm.nih.gov/pubmed/28264841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02582-16
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