The antioxidants resveratrol and N-acetylcysteine enhance anthelmintic activity of praziquantel and artesunate against Schistosoma mansoni

Abstract Background Treatment of schistosomiasis has relied on the anthelmintic drug praziquantel (PZQ) for more than a generation. Despite its celebrated performance for treatment and control of schistosomiasis and other platyhelminth infections, praziquantel has some shortcomings and the inability...

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Detalhes bibliográficos
Main Authors: Maria João Gouveia, Paul J. Brindley, Carlos Azevedo, Fátima Gärtner, José M. C. da Costa, Nuno Vale
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-06-01
Colecção:Parasites & Vectors
Assuntos:
Anthelmintic
Resveratrol
N-acetylcysteine
Biomolecules
Schistosomula
Schistosoma mansoni
Acesso em linha:http://link.springer.com/article/10.1186/s13071-019-3566-9
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