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Structural basis of mammalian mucin processing by the human gut O-glycopeptidase OgpA from Akkermansia muciniphila

Akkermansia muciniphila is a mucin-degrading bacterium commonly found in the human gut that promotes a beneficial effect on health, likely based on the regulation of mucus thickness and gut barrier integrity, but also on the modulation of the immune system. In this work, we focus in OgpA from A. muc...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Trastoy, Beatriz, Naegeli, Andreas, Anso, Itxaso, Sjögren, Jonathan, Guerin, Marcelo E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518263/
https://ncbi.nlm.nih.gov/pubmed/32973204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18696-y
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