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Structural basis of mammalian mucin processing by the human gut O-glycopeptidase OgpA from Akkermansia muciniphila

Akkermansia muciniphila is a mucin-degrading bacterium commonly found in the human gut that promotes a beneficial effect on health, likely based on the regulation of mucus thickness and gut barrier integrity, but also on the modulation of the immune system. In this work, we focus in OgpA from A. muc...

詳細記述

保存先:
書誌詳細
出版年:Nat Commun
主要な著者: Trastoy, Beatriz, Naegeli, Andreas, Anso, Itxaso, Sjögren, Jonathan, Guerin, Marcelo E.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518263/
https://ncbi.nlm.nih.gov/pubmed/32973204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18696-y
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