Pharmacological targeting of mitochondrial function and reactive oxygen species production prevents colon 26 cancer-induced cardiorespiratory muscle weakness

Cancer cachexia is a syndrome characterized by profound cardiac and diaphragm muscle wasting, which increase the risk of morbidity in cancer patients due to failure of the cardiorespiratory system. In this regard, muscle relies greatly on mitochondria to meet energy requirements for contraction and...

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Vydáno v:Oncotarget
Hlavní autoři: Smuder, Ashley J., Roberts, Brandon M., Wiggs, Michael P., Kwon, Oh Sung, Yoo, Jeung-Ki, Christou, Demetra D., Fuller, David D., Szeto, Hazel H., Judge, Andrew R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7517961/
https://ncbi.nlm.nih.gov/pubmed/33014286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27748
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