The Botanical Drug PBI-05204, a Supercritical CO(2) Extract of Nerium Oleander, Inhibits Growth of Human Glioblastoma, Reduces Akt/mTOR Activities, and Modulates GSC Cell-Renewal Properties

Glioblastoma multiform (GBM) is the most common primary glial tumor resulting in very low patient survival despite current extensive therapeutic efforts. Emerging evidence suggests that more effective treatments are required to overcome tumor heterogeneity, drug resistance and a complex tumor-suppor...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Pharmacol
Prif Awduron: Colapietro, Alessandro, Yang, Peiying, Rossetti, Alessandra, Mancini, Andrea, Vitale, Flora, Martellucci, Stefano, Conway, Tara L., Chakraborty, Sharmistha, Marampon, Francesco, Mattei, Vincenzo, Gravina, Giovanni Luca, Biordi, Assunta Leda, Wei, Daoyan, Newman, Robert A., Festuccia, Claudio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2020
Pynciau:
Pharmacology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7516200/
https://ncbi.nlm.nih.gov/pubmed/33013390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.552428
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