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An evaluation of overall survival in patients with newly diagnosed acute myeloid leukemia and the relationship with glasdegib treatment and exposure

PURPOSE: Glasdegib, an oral inhibitor of the Hedgehog signaling pathway, is approved in the United States in combination with low-dose cytarabine (LDAC) to treat patients with newly diagnosed acute myeloid leukemia (AML) ineligible to receive intensive chemotherapy. This population pharmacokinetic/p...

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Publicat a:Cancer Chemother Pharmacol
Autors principals: Lin, Swan, Shaik, Naveed, Chan, Geoffrey, Cortes, Jorge E., Ruiz-Garcia, Ana
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515941/
https://ncbi.nlm.nih.gov/pubmed/32885274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-020-04132-x
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