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Population Pharmacokinetics of Glasdegib in Patients With Advanced Hematologic Malignancies and Solid Tumors

Glasdegib is an inhibitor of the Hedgehog pathway recently approved in the United States for the treatment of acute myeloid leukemia. A population pharmacokinetic analysis was conducted to characterize the kinetic behavior of glasdegib and its sources of variability (covariates) by utilizing data fr...

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Bibliografski detalji
Izdano u:J Clin Pharmacol
Glavni autori: Lin, Swan, Shaik, Naveed, Martinelli, Giovanni, Wagner, Andrew J., Cortes, Jorge, Ruiz‐Garcia, Ana
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187372/
https://ncbi.nlm.nih.gov/pubmed/31769065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1556
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