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Population Pharmacokinetics of Glasdegib in Patients With Advanced Hematologic Malignancies and Solid Tumors

Glasdegib is an inhibitor of the Hedgehog pathway recently approved in the United States for the treatment of acute myeloid leukemia. A population pharmacokinetic analysis was conducted to characterize the kinetic behavior of glasdegib and its sources of variability (covariates) by utilizing data fr...

詳細記述

保存先:
書誌詳細
出版年:J Clin Pharmacol
主要な著者: Lin, Swan, Shaik, Naveed, Martinelli, Giovanni, Wagner, Andrew J., Cortes, Jorge, Ruiz‐Garcia, Ana
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187372/
https://ncbi.nlm.nih.gov/pubmed/31769065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1556
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