The neuropathic phenotype of the K/BxN transgenic mouse with spontaneous arthritis: pain, nerve sprouting and joint remodeling

The adult K/BxN transgenic mouse develops spontaneous autoimmune arthritis with joint remodeling and profound bone loss. We report that both males and females display a severe sustained tactile allodynia which is reduced by gabapentin but not the potent cyclooxygenase inhibitor ketorolac. In dorsal...

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Publicat a:Sci Rep
Autors principals: Gonçalves dos Santos, Gilson, Jimenéz-Andrade, Juan Miguel, Woller, Sarah A., Muñoz-Islas, Enriqueta, Ramírez-Rosas, Martha Beatriz, Ohashi, Nobuko, Ferreira Catroli, Glaucilene, Fujita, Yuya, Yaksh, Tony L., Corr, Maripat
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515905/
https://ncbi.nlm.nih.gov/pubmed/32973194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72441-5
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