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Loss of Murine FOXO3 in Cells of the Myeloid Lineage Enhances Myelopoiesis but Protects from K/BxN-Serum Transfer-Induced Arthritis

FOXO transcription factors have a highly conserved role in regulating transcription of genes involved in differentiation, cell cycle arrest, apoptosis and DNA repair. Loss of FOXO3 in mice has previously been shown to result in a myeloproliferative disease. In agreement with this, we found that an i...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kang, Hannah, Corr, Maripat, Mansson, Robert, Welinder, Eva, Hedrick, Stephen M., Stone, Erica L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430473/
https://ncbi.nlm.nih.gov/pubmed/25969990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126728
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