(18)F-FIBT may expand PET for β-amyloid imaging in neurodegenerative diseases

(18)F-FIBT, 2-(p-Methylaminophenyl)-7-(2-[(18)F]fluoroethoxy)imidazo-[2,1-b]benzothiazole, is a new selective PET tracer under clinical investigation to specifically image β-amyloid depositions (Aβ) in humans in-vivo that binds to Aβ with excellent affinity (K(d) 0.7 ± 0.2) and high selectivity over...

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Pubblicato in:Mol Psychiatry
Autori principali: Grimmer, Timo, Shi, Kuangyu, Diehl-Schmid, Janine, Natale, Bianca, Drzezga, Alexander, Förster, Stefan, Förstl, Hans, Schwaiger, Markus, Yakushev, Igor, Wester, Hans-Jürgen, Kurz, Alexander, Yousefi, Behrooz Hooshyar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515824/
https://ncbi.nlm.nih.gov/pubmed/30120417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-018-0203-5
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