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Linker region is required for efficient nuclear localization of polynucleotide kinase phosphatase

Polynucleotide kinase phosphatase (PNKP) is a DNA repair factor with dual enzymatic functions, i.e., phosphorylation of 5’-end and dephosphorylation of 3’-end, which are prerequisites for DNA ligation and, thus, is involved in multiple DNA repair pathways, i.e., base excision repair, single-strand b...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tsukada, Kaima, Matsumoto, Yoshihisa, Shimada, Mikio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7514006/
https://ncbi.nlm.nih.gov/pubmed/32970693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239404
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