Flavopiridol causes cell cycle inhibition and demonstrates anti-cancer activity in anaplastic thyroid cancer models

Anaplastic thyroid cancer (ATC) is a rare, but nearly uniformly fatal disease that is typically resistant to chemotherapy and radiation. Alternative strategies to target this cancer at a molecular level are necessary in order to improve dismal outcomes for ATC patients. We examined the effects of fl...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Pinto, Nicole, Prokopec, Stephenie D., Ghasemi, Farhad, Meens, Jalna, Ruicci, Kara M., Khan, Imran M., Mundi, Neil, Patel, Krupal, Han, Myung W., Yoo, John, Fung, Kevin, MacNeil, Danielle, Mymryk, Joe S., Datti, Alessandro, Barrett, John W., Boutros, Paul C., Ailles, Laurie, Nichols, Anthony C.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7514001/
https://ncbi.nlm.nih.gov/pubmed/32970704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239315
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