DIETARY METHIONINE RESTRICTION SIGNALS TO THE BRAIN THROUGH FGF21 TO REGULATE ENERGY BALANCE AND REMODELING OF ADIPOSE TISSUE

OBJECTIVE: Restricting dietary methionine to 0.17% in mice increases energy expenditure, reduces fat deposition, and improves metabolic health by increasing hepatic FGF21. The goal was to compare each of these responses in mice with the co-receptor for FGF21 deleted in either adipose tissue or the b...

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Veröffentlicht in:Obesity (Silver Spring)
Hauptverfasser: Forney, LA, Fang, H, Sims, LC, Stone, KP, Vincik, LY, Vick, AM, Gibson, AN, Burk, DH, Gettys, TW
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7513464/
https://ncbi.nlm.nih.gov/pubmed/32959519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.22919
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