DNA Thermo-Protection Facilitates Whole-Genome Sequencing of Mycobacteria Direct from Clinical Samples

Mycobacterium tuberculosis is the leading cause of death from bacterial infection. Improved rapid diagnosis and antimicrobial resistance determination, such as by whole-genome sequencing, are required. Our aim was to develop a simple, low-cost method of preparing DNA for sequencing direct from M. tu...

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Detalhes bibliográficos
Publicado no:J Clin Microbiol
Main Authors: George, Sophie, Xu, Yifei, Rodger, Gillian, Morgan, Marcus, Sanderson, Nicholas D., Hoosdally, Sarah J., Thulborn, Samantha, Robinson, Esther, Rathod, Priti, Walker, A. Sarah, Peto, Timothy E. A., Crook, Derrick W., Dingle, Kate E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Mycobacteriology and Aerobic Actinomycetes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7512152/
https://ncbi.nlm.nih.gov/pubmed/32719032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00670-20
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