Evaluation of Whole-Genome Sequencing for Mycobacterial Species Identification and Drug Susceptibility Testing in a Clinical Setting: a Large-Scale Prospective Assessment of Performance against Line Probe Assays and Phenotyping

Use of whole-genome sequencing (WGS) for routine mycobacterial species identification and drug susceptibility testing (DST) is becoming a reality. We compared the performances of WGS and standard laboratory workflows prospectively, by parallel processing at a major mycobacterial reference service ov...

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Pubblicato in:J Clin Microbiol
Autori principali: Quan, T. Phuong, Bawa, Zharain, Foster, Dona, Walker, Tim, del Ojo Elias, Carlos, Rathod, Priti, Iqbal, Zamin, Bradley, Phelim, Mowbray, Janet, Walker, A. Sarah, Crook, Derrick W., Wyllie, David H., Peto, Timothy E. A., Smith, E. Grace
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
Soggetti:
Mycobacteriology and Aerobic Actinomycetes
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786738/
https://ncbi.nlm.nih.gov/pubmed/29167290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01480-17
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