Genetic driver mutations introduced in identical cell-of-origin in murine glioblastoma reveal distinct immune landscapes but similar response to checkpoint blockade

Glioblastoma (GBM) is the most aggressive primary brain tumor. In addition to being genetically heterogeneous, GBMs are also immunologically heterogeneous. However, whether the differences in immune microenvironment are driven by genetic driver mutation is unexplored. By leveraging the versatile RCA...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Glia
Egile Nagusiak: Chen, Zhihong, Herting, Cameron J., Ross, James L., Gabanic, Ben, Vallcorba, Montse Puigdelloses, Szulzewsky, Frank, Wojciechowicz, Megan L., Cimino, Patrick J., Ezhilarasan, Ravesanker, Sulman, Erik P., Ying, Mingyao, Ma’ayan, Avi, Read, Renee D., Hambardzumyan, Dolores
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7512141/
https://ncbi.nlm.nih.gov/pubmed/32639068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23883
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak