TrkB phosphorylation by Cdk5 is required for activity-dependent structural plasticity and spatial memory

The neurotrophin brain-derived neurotrophic factor (BDNF) and its receptor TrkB participate in diverse neuronal functions, including activity-dependent synaptic plasticity that is crucial for learning and memory. On binding to BDNF, TrkB is not only autophosphorylated at tyrosine residues but also u...

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Detalhes bibliográficos
Publicado no:Nat Neurosci
Main Authors: Lai, Kwok-On, Wong, Alan S L, Cheung, Man-Chun, Xu, Pei, Liang, Zhuoyi, Lok, Ka-Chun, Xie, Hui, Palko, Mary E, Yung, Wing-Ho, Tessarollo, Lino, Cheung, Zelda H, Ip, Nancy Y
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511999/
https://ncbi.nlm.nih.gov/pubmed/23064382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3237
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