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Hematopoietic Stem Cell Transplantation and Vasculopathy Associated With STAT3-Dominant-Negative Hyper-IgE Syndrome

Dominant negative mutations in the transcription-factor STAT3 underlie the rare primary immunodeficiency Job's syndrome. Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) has shown promise in correction of the underlying immunological defect, with one report suggesting HSCT can prevent...

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Dades bibliogràfiques
Publicat a:Front Pediatr
Autors principals: Ponsford, Mark J., Clark, James, Mock, Joel, Abinun, Mario, Carne, Emily, El-Shanawany, Tariq, Williams, Paul E., Choudhury, Anirban, Freeman, Alexandra F., Gennery, Andrew R., Jolles, Stephen
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Pediatrics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511721/
https://ncbi.nlm.nih.gov/pubmed/33014947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2020.00575
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