Hematopoietic Stem Cell Transplantation and Vasculopathy Associated With STAT3-Dominant-Negative Hyper-IgE Syndrome

Dominant negative mutations in the transcription-factor STAT3 underlie the rare primary immunodeficiency Job's syndrome. Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) has shown promise in correction of the underlying immunological defect, with one report suggesting HSCT can prevent...

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Bibliographische Detailangaben
Veröffentlicht in:Front Pediatr
Hauptverfasser: Ponsford, Mark J., Clark, James, Mock, Joel, Abinun, Mario, Carne, Emily, El-Shanawany, Tariq, Williams, Paul E., Choudhury, Anirban, Freeman, Alexandra F., Gennery, Andrew R., Jolles, Stephen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Pediatrics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511721/
https://ncbi.nlm.nih.gov/pubmed/33014947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2020.00575
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