Genome wide association study in 3,173 outbred rats identifies multiple loci for body weight, adiposity, and fasting glucose

OBJECTIVE: Obesity is influenced by genetic and environmental factors. Despite success of human genome wide association studies (GWAS), the specific genes that confer obesity remain largely unknown. The objective of this study was to use outbred rats to identify genetic loci underlying obesity and r...

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Publicat a:Obesity (Silver Spring)
Autors principals: Chitre, Apurva S., Polesskaya, Oksana, Holl, Katie, Gao, Jianjun, Cheng, Riyan, Bimschleger, Hannah, Martinez, Angel Garcia, George, Tony, Gileta, Alexander F., Han, Wenyan, Horvath, Aidan, Hughson, Alesa, Ishiwari, Keita, King, Christopher P., Lamparelli, Alexander, Versaggi, Cassandra L., Martin, Connor, St. Pierre, Celine L., Tripi, Jordan A., Wang, Tengfei, Chen, Hao, Flagel, Shelly B., Meyer, Paul, Richards, Jerry, Robinson, Terry E., Palmer, Abraham A., Woods, Leah C. Solberg
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511439/
https://ncbi.nlm.nih.gov/pubmed/32860487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.22927
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