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Ancestral sequence reconstruction produces thermally stable enzymes with mesophilic enzyme-like catalytic properties

Enzymes have high catalytic efficiency and low environmental impact, and are therefore potentially useful tools for various industrial processes. Crucially, however, natural enzymes do not always have the properties required for specific processes. It may be necessary, therefore, to design, engineer...

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Publicat a:Sci Rep
Autors principals: Furukawa, Ryutaro, Toma, Wakako, Yamazaki, Koji, Akanuma, Satoshi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511310/
https://ncbi.nlm.nih.gov/pubmed/32968141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72418-4
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