Teclistamab is an active T cell–redirecting bispecific antibody against B-cell maturation antigen for multiple myeloma

B-cell maturation antigen (BCMA), a member of the tumor necrosis factor family of receptors, is predominantly expressed on the surface of terminally differentiated B cells. BCMA is highly expressed on plasmablasts and plasma cells from multiple myeloma (MM) patient samples. We developed a BCMAxCD3 b...

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Veröffentlicht in:Blood Adv
Hauptverfasser: Pillarisetti, Kodandaram, Powers, Gordon, Luistro, Leopoldo, Babich, Alexander, Baldwin, Eric, Li, Yingzhe, Zhang, Xiaochun, Mendonça, Mark, Majewski, Nate, Nanjunda, Rupesh, Chin, Diana, Packman, Kathryn, Elsayed, Yusri, Attar, Ricardo, Gaudet, François
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2020
Schlagworte:
Immunobiology and Immunotherapy
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7509877/
https://ncbi.nlm.nih.gov/pubmed/32956453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002393
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