A T-cell–redirecting bispecific G-protein–coupled receptor class 5 member D x CD3 antibody to treat multiple myeloma

T-cell–mediated approaches have shown promise in myeloma treatment. However, there are currently a limited number of specific myeloma antigens that can be targeted, and multiple myeloma (MM) remains an incurable disease. G-protein–coupled receptor class 5 member D (GPRC5D) is expressed in MM and smo...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Pillarisetti, Kodandaram, Edavettal, Suzanne, Mendonça, Mark, Li, Yingzhe, Tornetta, Mark, Babich, Alexander, Majewski, Nate, Husovsky, Matt, Reeves, Dara, Walsh, Eileen, Chin, Diana, Luistro, Leopoldo, Joseph, Jocelin, Chu, Gerald, Packman, Kathryn, Shetty, Shoba, Elsayed, Yusri, Attar, Ricardo, Gaudet, François
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Immunobiology and Immunotherapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7146017/
https://ncbi.nlm.nih.gov/pubmed/32040549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019003342
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