Myeloperoxidase instigates proinflammatory responses in a cecal ligation and puncture rat model of sepsis

Myeloperoxidase (MPO)-derived hypochlorous (HOCl) reacts with membrane plasmalogens to yield α-chlorofatty aldehydes such as 2-chlorofatty aldehyde (2-ClFALD) and its metabolite 2-chlorofatty acid (2-ClFA). Recent studies showed that 2-ClFALD and 2-ClFA serve as mediators of the inflammatory respons...

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Xehetasun bibliografikoak
Argitaratua izan da:Am J Physiol Heart Circ Physiol
Egile Nagusiak: Yu, Hong, Liu, Yajun, Wang, Meifang, Restrepo, Ricardo J., Wang, Derek, Kalogeris, Theodore J., Neumann, William L., Ford, David A., Korthuis, Ronald J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2020
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7509276/
https://ncbi.nlm.nih.gov/pubmed/32762560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00440.2020
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